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Kinetic Mechanisms of Enzyme Inhibition and Activation
Tutorials, examples, mechanism validation, and advice for publishing
Introduction
Mechanisms
Inhibition and nonessential activation
Essential activation
Data analysis
Raw data
Concentration-dependence of parameters
Fingerprints parameters
The specific velocity plot
Fingerprints specific velocity plot
The final polish
Tightly-bound modifiers
A word on software
Published examples
LSpI
LCaI
LMx(Sp > Ca)I
Parabolic inhibition
LMx(Sp < Ca)I
LMx(Sp = Ca)I
HSpI
HMx(Sp > Ca)I
HCaI
HMx(Sp < Ca)I
HMx(Sp = Ca)I
HMxD(I / A)
HCaA
HMx(Sp > Ca)A
HMxD(A / I)
HSpA
HMx(Sp < Ca)A
HMx(Sp = Ca)A
List of all examples
Data validation
Words of advice
Constructive criticism
About/Contact
Contact
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