Type 1

Your data show that kcat and obviously also 1/kcat are independent of modifier concentration, namely

This property is shared by tree basic modifier mechanisms, which can be distinguished from one another from the dependencies of Km on modifier concentration, [X]. Click the appropriate statement below to unravel the mechanism.


Km increases linearly

The sought mechanism is:

Linear specific inhibition, LSpI

Examples of LSpI

Km increases as hyperbola

The sought mechanism is:

Hyperbolic specific inhibition, HSpI

Examples of HSpI


Km decreases as hyperbola

The sought mechanism is:

Hyperbolic specific activation, HSpA

Examples of HSpA

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